ISSYS Awarded New Fabrication Patents for Micro-Tubes

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Ypsilanti, Mich. — Integrated Sensing Systems Inc. (ISSYS) announces that the U.S Patent Office has granted a new design and fabrication patent entitled "Micromachined Fluidic Apparatus" (US Patent No. 6,477,901), which covers the manufacturing of stationary and free-standing micro-tubes as small as one-tenth of the thickness of a human hair.

This patent provides a new technology tool for integration of MEMS (microelectromechanical systems) into new and more accurate industrial/scientific instruments and medical device products that enhance the quality of life and mobility of the patient, including micro-density meters, micro-flow sensors and portable multiple-drug delivery systems. This patented micro-tube core technology will first be used in the manufacture of a new highly accurate scientific and portable measuring instrument for specific gravity (density) measurements in pharmaceutical and petroleum quality control and research labs. A beta ISSYS micro density meter proto type is planned for launch in 2003 with the benefits of temperature control micro-liter samples for decrease costs and impact on the environment.In addition, ISSYS strategic business plan calls for the use of this patent in the launching of a series of medical device products over the next two years that will lead to a portable, highly-accurate, multiple-drug infusion system for use in the fight against AIDS and cancer.ISSYS has two more issued and 25 pending patents covering a wide spectrum for the design, fabrication, packaging, and applications of MEMS for medical, fluidic and analytical products. It has also licensed eight patents from the University of Michigan, five exclusively.In addition to its patents, ISSYS derives protection from its know how, particularly in the back-end processes, assembly, packaging and high-quality manufacturing areas. For more information, visit



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